Hematopoiesis

Comparison of hematopoietic stem cells derived from fresh and cryopreserved whole cord blood in the generation of humanized mice. Scholbach J, Schulz A, Westphal F, Egger D, Wege AK, Patties I, Köberle M, Sack U, Lange F. PLoS One. 2012;7(10):e46772. doi: 10.1371/journal.pone.0046772. Epub 2012 Oct 11. PMID: 23071634

Antibody Repertoires in Humanized NOD-scid-IL2R?(null) Mice and Human B Cells Reveals Human-Like Diversification and Tolerance Checkpoints in the Mouse.  Ippolito GC, Hoi KH, Reddy ST, Carroll SM, Ge X, Rogosch T, Zemlin M, Shultz LD, Ellington AD, Vandenberg CL, Georgiou G.  PLoS One. 2012;7(4):e35497. Epub 2012 Apr 27. PMID: 22558161

Hematopoiesis: a human perspective.  Doulatov S, Notta F, Laurenti E, Dick JE.  Cell Stem Cell. 2012 Feb 3;10(2):120-36.  PMID: 22305562

Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.  Strowig T, Rongvaux A, Rathinam C, Takizawa H, Borsotti C, Philbrick W, Eynon EE, Manz MG, Flavell RA.  Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13218-23. Epub 2011 Jul 25.  PMID: 21788509

Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo.  Rongvaux A, Willinger T, Takizawa H, Rathinam C, Auerbach W, Murphy AJ, Valenzuela DM, Yancopoulos GD, Eynon EE, Stevens S, Manz MG, Flavell RA.  Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2378-83. Epub 2011 Jan 24.  PMID: 21262827

Renaissance for mouse models of human hematopoiesis and immunobiology.  Manz MG, Di Santo JP.  Nat Immunol. 2009 Oct;10(10):1039-42. Review.  PMID: 19767720